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io.github.cyanheads/pharmacogenomics-guidelines-mcp-server

io.github.cyanheads/pharmacogenomics-guidelines-mcp-servercyanheadsstreamable-httpv0.2.1Scanned

Find pharmacogenomics guidelines, translate diplotypes, and retrieve prescribing recommendations.

6 tools: 6 only read.

Tools: 0 delete, 0 irreversible, 0 write, 6 read.
  • Reads private data · 0
  • Reads text others write · 6
  • Can send data out · 0
  • No findings

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Tools

Grouped by what each tool does, most consequential first. Open one for its reasons and full description; descriptions are the publisher's own words.

6 tools

Only reads 6Show 6 read-only tools
  • pgx_get_guidelineRetrieve guideline coverage by source ID, exact gene symbol or exact drug name/ID.Reads text others writeNo findings

    Why it is in this group

    • The name "pgx_get_guideline" says "get": a word for reading.

    What it can reach

    • untrusted-inputThe server marks it openWorldHint: true: it reaches things outside the server's own data.
    Description, as the server wrote it
    Retrieve guideline coverage by source ID, exact gene symbol or exact drug name/ID. Default summary pages complete guideline records with exact drugCount/pairCount. view=drugs or pairs requires by=id and pages only that related collection, retaining its guideline descriptor. Ambiguous drug names page candidates for retry with drugId. Follow page.nextOffset; the 24,000-byte soft budget cuts only between complete rows, with oversizedRow for an indivisible exception. Missing coverage is found=false. Consult linked guidelines before clinical use.

    Annotations the server declares

    • readOnlyHint: true
    • idempotentHint: true
    • openWorldHint: true
  • pgx_get_recommendationsBrowse CPIC recommendations in drug mode with one exact drugName or drugId.Reads text others writeNo findings

    Why it is in this group

    • The name "pgx_get_recommendations" says "get": a word for reading.

    What it can reach

    • untrusted-inputThe server marks it openWorldHint: true: it reaches things outside the server's own data.
    • untrusted-inputThe description's first sentence says "browse": it reads web pages, which anyone can write.
    Description, as the server wrote it
    Browse CPIC recommendations in drug mode with one exact drugName or drugId. Match across drugs in results mode with geneResults or geneSymbol plus phenotype/activityScore, or genotype mode with 1–10 uniquely resolved gene/diplotype entries. Both matching modes accept an optional drug. Optional view=test_alerts selects complete example CDS alerts instead of recommendations, without joins; default view=recommendations. Alert records retain ordered alerttext, No CDS and n/a. Use pgx_list_reference topic phenotypes for source values. Every matched prerequisite must be explicit; omitted genes are never normal, negative or No Result. Preserve populations, scores, classifications and source text. Follow page.nextOffset and incompletePage.nextOffset independently for the selected collection and missing-gene diagnostics; consult source guidelines before clinical use.

    Annotations the server declares

    • readOnlyHint: true
    • idempotentHint: true
    • openWorldHint: true
  • pgx_list_referenceInspect gene symbols, gene-specific source results, CPIC levels, ClinPGx testing labels, recommendation classifications and input formats.Reads text others writeNo findings

    Why it is in this group

    • The name "pgx_list_reference" says "list": a word for reading.

    What it can reach

    • untrusted-inputThe server marks it openWorldHint: true: it reaches things outside the server's own data.
    Description, as the server wrote it
    Inspect gene symbols, gene-specific source results, CPIC levels, ClinPGx testing labels, recommendation classifications and input formats. phenotypes requires geneSymbol and preserves distinct activity-score rows, frequencies and consultation text. Live genes/phenotypes support paging; static topics return their complete vocabulary without upstream requests. Use returned values in subsequent discovery, diplotype and recommendation calls.

    Annotations the server declares

    • readOnlyHint: true
    • idempotentHint: true
    • openWorldHint: true
  • pgx_lookup_diplotypeTranslate a CPIC-supported diplotype or allele-status result for one gene.Reads text others writeNo findings

    Why it is in this group

    • The name "pgx_lookup_diplotype" says "lookup": a word for reading.

    What it can reach

    • untrusted-inputThe server marks it openWorldHint: true: it reaches things outside the server's own data.
    Description, as the server wrote it
    Translate a CPIC-supported diplotype or allele-status result for one gene. Supply geneSymbol and exact diplotype notation, including star alleles, named HLA positive/negative statuses, or non-star sequences; use pgx_search_alleles and pgx_list_reference with topic phenotypes to inspect supported values. Exact lookup precedes bounded reverse-order or status aliases. Multiple source rows remain ambiguous; no activity score or missing gene result is inferred.

    Annotations the server declares

    • readOnlyHint: true
    • idempotentHint: true
    • openWorldHint: true
  • pgx_search_allelesInspect CPIC allele function, evidence, definition metadata and complete population frequencies for geneSymbol.Reads text others writeNo findings

    Why it is in this group

    • The name "pgx_search_alleles" says "search": a word for reading.

    What it can reach

    • untrusted-inputThe server marks it openWorldHint: true: it reaches things outside the server's own data.
    Description, as the server wrote it
    Inspect CPIC allele function, evidence, definition metadata and complete population frequencies for geneSymbol. Name matches literally first, then a matching gene prefix before a star allele may be removed; clinicalFunctionalStatus matches literal text case-insensitively. Discover genes with pgx_list_reference. Definitions are metadata, not variant interpretation. Frequencies are source fractions; inferred frequencies are not observations and do not establish individual risk. Pages have a 24,000-byte complete-result soft budget; an indivisible exception sets oversizedRow. Continue with page.nextOffset.

    Annotations the server declares

    • readOnlyHint: true
    • idempotentHint: true
    • openWorldHint: true
  • pgx_search_pairsSearch evaluated gene–drug pairs by gene, literal drug-name substring, exact drug/RxNorm/ATC identifiers, evaluation level or testing label.Reads text others writeNo findings

    Why it is in this group

    • The name "pgx_search_pairs" says "search": a word for reading.

    What it can reach

    • untrusted-inputThe server marks it openWorldHint: true: it reaches things outside the server's own data.
    Description, as the server wrote it
    Search evaluated gene–drug pairs by gene, literal drug-name substring, exact drug/RxNorm/ATC identifiers, evaluation level or testing label. Filters combine with AND; identifiers never fall back to name-only search. Results include source drug identifiers and guideline links for pgx_get_guideline. A pair evaluation is not a prescribing recommendation. Follow nextOffset to continue.

    Annotations the server declares

    • readOnlyHint: true
    • idempotentHint: true
    • openWorldHint: true

This is not a safety rating, and no finding is not a safety guarantee. The groups and findings come from fixed checks of the tool definitions the server returned on the date shown, not from its code or what it does when called. How the checks work.

Exfil surface

Which tools read private data, which read text someone else can write, and which can send data out. One of each is a path a prompt injection can use.

No private-data, untrusted-input, outbound path in this server alone: no tool is tagged private-data or outbound.

Reads private data0
Reads files, mail, messages, databases, secrets, calendars or repositories.
Reads text others write6
Brings in text someone else can write: web pages, inbound email, messages, issues and comments.
Can send data out0
Can carry data to people or systems: it sends, posts or publishes, or takes a recipient, channel or URL.

Other servers in the same agent add their own tools to these paths. Audit your whole setup to see them together.

Findings

Matches of fixed checks, with the text they matched.

No check matched anything in these tool definitions. That is not a safety guarantee.

History

Changes to its tool definitions and to its remote endpoint, newest first.

No change seen yet. Its tools are rescanned every day, and a remote endpoint is looked at once a week.

All changes to this server

Install

Pinned to version 0.2.1. Values in angle brackets are yours to fill in.

claude mcp add --transport http pharmacogenomics-guidelines https://pharmacogenomics-guidelines.caseyjhand.com/mcp
claude mcp add --transport http pharmacogenomics-guidelines https://pharmacogenomics-guidelines.caseyjhand.com/mcp

Run in a terminal.

Claude Code permissions

Allow the reads, ask before a change or a way out, deny the deletes. Paste into .claude/settings.json.

.claude/settings.json
{
  "permissions": {
    "allow": [
      "mcp__pharmacogenomics-guidelines__pgx_search_pairs",
      "mcp__pharmacogenomics-guidelines__pgx_get_guideline",
      "mcp__pharmacogenomics-guidelines__pgx_lookup_diplotype",
      "mcp__pharmacogenomics-guidelines__pgx_get_recommendations",
      "mcp__pharmacogenomics-guidelines__pgx_search_alleles",
      "mcp__pharmacogenomics-guidelines__pgx_list_reference"
    ],
    "ask": [],
    "deny": []
  }
}

Tools that only read are allowed, tools that change things ask first, tools that delete or cancel are denied. A read that can send data out (it takes a URL, say) asks first too. It assumes the server is installed as pharmacogenomics-guidelines. Review it before you use it.

Capability tags behind 6 rules
  • mcp__pharmacogenomics-guidelines__pgx_search_pairs untrusted-input
  • mcp__pharmacogenomics-guidelines__pgx_get_guideline untrusted-input
  • mcp__pharmacogenomics-guidelines__pgx_lookup_diplotype untrusted-input
  • mcp__pharmacogenomics-guidelines__pgx_get_recommendations untrusted-input
  • mcp__pharmacogenomics-guidelines__pgx_search_alleles untrusted-input
  • mcp__pharmacogenomics-guidelines__pgx_list_reference untrusted-input

Pin

Keep the decision: fail CI when the tools change, follow every change, or show a badge.

Pin in CI

Fail a build when the tools you reviewed are not the tools the server serves today.

curl -s "https://anlyon.dev/api/v1/servers/io.github.cyanheads/pharmacogenomics-guidelines-mcp-server/verify?hash=9ebf8dcd0abbb977989999c7bf175b37fd7d28196107cfd5532ed4bd1da65597" | jq -e '.changed == false'

Pinned hash 9ebf8dcd0abb, from Oct 24, 2026, 22:18 UTC.

Watch

Get told when its tools change: a new tool, a new description, a new class.

https://anlyon.dev/servers/io.github.cyanheads/pharmacogenomics-guidelines-mcp-server/changes.xml

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Source: MCP Registry · repository. Synced Oct 24, 2026, 22:17 UTC.