io.github.cyanheads/interpro-mcp-server
io.github.cyanheads/interpro-mcp-servercyanheadsstreamable-httpv0.1.2Scanned
Search InterPro entries, map protein domains and functional sites, and find proteins by domain.
6 tools: 6 only read.
- Reads private data · 5
- Reads text others write · 6
- Can send data out · 0
- No findings
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Import an OpenAPI spec →Tools
Grouped by what each tool does, most consequential first. Open one for its reasons and full description; descriptions are the publisher's own words.
6 tools
Only reads 6Show 6 read-only tools
interpro_find_proteins_by_domainFind UniProt proteins carrying an InterPro or member signature.Reads private dataReads text others writeNo findings
Why it is in this group
- The name "interpro_find_proteins_by_domain" says "find": a word for reading.
What it can reach
- private-dataThe input names a database (input.sourceDatabase), and the tool reads: it reads databases.
- untrusted-inputThe server marks it openWorldHint: true: it reaches things outside the server's own data.
Description, as the server wrote it Find UniProt proteins carrying an InterPro or member signature. Defaults to reviewed human proteins; reviewedOnly=false includes reviewed and unreviewed proteins in the chosen taxon. Optional isFragment filters fragment annotations; false does not prove a complete canonical sequence.
Annotations the server declares
- readOnlyHint: true
- idempotentHint: true
- openWorldHint: true
interpro_get_clanRetrieve a Pfam, CDD, or PIRSF clan/set and a cursor page of member entries; optionally include its relationship graph, returned in slices that fit the response budget and paged wi…Reads private dataReads text others writeNo findings
Why it is in this group
- The name "interpro_get_clan" says "get": a word for reading.
What it can reach
- private-dataThe input names a database (input.sourceDatabase), and the tool reads: it reads databases.
- untrusted-inputThe server marks it openWorldHint: true: it reaches things outside the server's own data.
Description, as the server wrote it Retrieve a Pfam, CDD, or PIRSF clan/set and a cursor page of member entries; optionally include its relationship graph, returned in slices that fit the response budget and paged with relationshipOffset.
Annotations the server declares
- readOnlyHint: true
- idempotentHint: true
- openWorldHint: true
interpro_get_entryRetrieve one InterPro or member-database entry, including description, hierarchy, member signatures, GO terms, literature, cross-references, clan membership, and coverage counters.Reads private dataReads text others writeNo findings
Why it is in this group
- The name "interpro_get_entry" says "get": a word for reading.
What it can reach
- private-dataThe description's first sentence says "retrieve" and "database": it reads databases.
- private-dataThe input names a database (input.sourceDatabase), and the tool reads: it reads databases.
- untrusted-inputThe server marks it openWorldHint: true: it reaches things outside the server's own data.
Description, as the server wrote it Retrieve one InterPro or member-database entry, including description, hierarchy, member signatures, GO terms, literature, cross-references, clan membership, and coverage counters.
Annotations the server declares
- readOnlyHint: true
- idempotentHint: true
- openWorldHint: true
interpro_get_protein_domainsRetrieve InterPro and member-signature matches on a canonical UniProt protein, preserving every location and discontinuous fragment.Reads text others writeNo findings
Why it is in this group
- The name "interpro_get_protein_domains" says "get": a word for reading.
What it can reach
- untrusted-inputThe server marks it openWorldHint: true: it reaches things outside the server's own data.
Description, as the server wrote it Retrieve InterPro and member-signature matches on a canonical UniProt protein, preserving every location and discontinuous fragment. Optionally retain matches covering a residue and include extra predicted features. Large maps arrive in segments of whole matches that fit the response budget: the first segment carries the protein metadata, requested extra features follow the last match, and coverage.nextCursor continues until hasMore is false.
Annotations the server declares
- readOnlyHint: true
- idempotentHint: true
- openWorldHint: true
interpro_list_referenceList supported InterPro database slugs, entry types, accession routing patterns, common taxon IDs, or current release information.Reads private dataReads text others writeNo findings
Why it is in this group
- The name "interpro_list_reference" says "list": a word for reading.
What it can reach
- private-dataThe description's first sentence says "list" and "database": it reads databases.
- untrusted-inputThe server marks it openWorldHint: true: it reaches things outside the server's own data.
Description, as the server wrote it List supported InterPro database slugs, entry types, accession routing patterns, common taxon IDs, or current release information.
Annotations the server declares
- readOnlyHint: true
- idempotentHint: true
- openWorldHint: true
interpro_search_entriesSearch InterPro entries or member signatures by text or entry type.Reads private dataReads text others writeNo findings
Why it is in this group
- The name "interpro_search_entries" says "search": a word for reading.
What it can reach
- private-dataThe input names a database (input.sourceDatabase), and the tool reads: it reads databases.
- untrusted-inputThe server marks it openWorldHint: true: it reaches things outside the server's own data.
Description, as the server wrote it Search InterPro entries or member signatures by text or entry type. GO filters require sourceDatabase interpro; integratedInto selects member signatures for an InterPro accession. Results are cursor-paged; use interpro_get_entry for full metadata.
Annotations the server declares
- readOnlyHint: true
- idempotentHint: true
- openWorldHint: true
This is not a safety rating, and no finding is not a safety guarantee. The groups and findings come from fixed checks of the tool definitions the server returned on the date shown, not from its code or what it does when called. How the checks work.
Exfil surface
Which tools read private data, which read text someone else can write, and which can send data out. One of each is a path a prompt injection can use.
No private-data, untrusted-input, outbound path in this server alone: no tool is tagged outbound.
- Reads private data5
- Reads files, mail, messages, databases, secrets, calendars or repositories.
- Reads text others write6
- Brings in text someone else can write: web pages, inbound email, messages, issues and comments.
- Can send data out0
- Can carry data to people or systems: it sends, posts or publishes, or takes a recipient, channel or URL.
Other servers in the same agent add their own tools to these paths. Audit your whole setup to see them together.
Findings
Matches of fixed checks, with the text they matched.
No check matched anything in these tool definitions. That is not a safety guarantee.
History
Changes to its tool definitions and to its remote endpoint, newest first.
No change seen yet. Its tools are rescanned every day, and a remote endpoint is looked at once a week.
Install
Pinned to version 0.1.2. Values in angle brackets are yours to fill in.
claude mcp add --transport http interpro https://interpro.caseyjhand.com/mcpclaude mcp add --transport http interpro https://interpro.caseyjhand.com/mcpRun in a terminal.
Claude Code permissions
Allow the reads, ask before a change or a way out, deny the deletes. Paste into .claude/settings.json.
{
"permissions": {
"allow": [
"mcp__interpro__interpro_list_reference",
"mcp__interpro__interpro_search_entries",
"mcp__interpro__interpro_get_entry",
"mcp__interpro__interpro_get_clan",
"mcp__interpro__interpro_get_protein_domains",
"mcp__interpro__interpro_find_proteins_by_domain"
],
"ask": [],
"deny": []
}
}Tools that only read are allowed, tools that change things ask first, tools that delete or cancel are denied. A read that can send data out (it takes a URL, say) asks first too. It assumes the server is installed as interpro. Review it before you use it.
Capability tags behind 6 rules
- mcp__interpro__interpro_list_reference private-data, untrusted-input
- mcp__interpro__interpro_search_entries private-data, untrusted-input
- mcp__interpro__interpro_get_entry private-data, untrusted-input
- mcp__interpro__interpro_get_clan private-data, untrusted-input
- mcp__interpro__interpro_get_protein_domains untrusted-input
- mcp__interpro__interpro_find_proteins_by_domain private-data, untrusted-input
Pin
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Pin in CI
Fail a build when the tools you reviewed are not the tools the server serves today.
curl -s "https://anlyon.dev/api/v1/servers/io.github.cyanheads/interpro-mcp-server/verify?hash=da5f94dd1f34e0f2ac4d6487e79929664673da87cbbe764be65df81283b03406" | jq -e '.changed == false'Pinned hash da5f94dd1f34, from Oct 24, 2026, 09:18 UTC.
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https://anlyon.dev/servers/io.github.cyanheads/interpro-mcp-server/changes.xmlAn Atom feed. Works in any feed reader or Slack's RSS app.
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[](https://anlyon.dev/servers/io.github.cyanheads/interpro-mcp-server)Source: MCP Registry · repository. Synced Oct 24, 2026, 09:17 UTC.