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ivive.app

by ivive.app · remote · no sign-in to list tools · v1.0.2 · published by app.ivive

Human hepatic clearance from in-vitro CLint, with the error band measured on known drugs.

Changes · 6
CompareRegistry entry

6 tools: 6 change things.

Scanned Oct 21, 2026

No check matched anything in the tool definitions. No finding is not a safety guarantee. How the checks work.

claude mcp add --transport http ivive https://api.ivive.app/mcp/

Tools

Open a tool for its reasons and full description. Descriptions are the publisher's own words, shown as they are.

6 tools

Changes things 6Claude Code: ask
  • calc_clhepHepatic and plasma clearance from in-vitro CLint, fu,mic and fu,p (IVIVE), with the observed-CL band and applicability warnings.No findings

    Why it is in this group

    • Nothing in its name or description says what it does, so it is counted as a write.
    Description, as the server wrote it
    Hepatic and plasma clearance from in-vitro CLint, fu,mic and fu,p (IVIVE), with the observed-CL band and applicability warnings. If fu,p or fu,mic came from predict_inputs, tell the user the result rests on predicted inputs.
  • input_sensitivityHow far plasma CL moves as each input is varied over a range, e.g.No findings

    Why it is in this group

    • Nothing in its name or description says what it does, so it is counted as a write.
    Description, as the server wrote it
    How far plasma CL moves as each input is varied over a range, e.g. a predicted fu,p over its 50% range.
  • predict_inputsPredict fu,p and fu,inc from a SMILES, with structure-only human CL and Vss as second opinions.No findings

    Why it is in this group

    • Nothing in its name or description says what it does, so it is counted as a write.
    Description, as the server wrote it
    Predict fu,p and fu,inc from a SMILES, with structure-only human CL and Vss as second opinions. Predictions, not measurements; check the applicability verdict.
  • scale_to_humanPredict human plasma CL from observed animal in-vivo CL (rat, dog, monkey), every applicable method with its measured error.No findings

    Why it is in this group

    • Nothing in its name or description says what it does, so it is counted as a write.
    Description, as the server wrote it
    Predict human plasma CL from observed animal in-vivo CL (rat, dog, monkey), every applicable method with its measured error. Observed animal CL only, never predicted.
  • similar_drugsNearest reference drugs to a SMILES (Tanimoto, Morgan radius 2), each with measured human plasma CL and the CL IVIVE predicted from its measured inputs.No findings

    Why it is in this group

    • Nothing in its name or description says what it does, so it is counted as a write.
    Description, as the server wrote it
    Nearest reference drugs to a SMILES (Tanimoto, Morgan radius 2), each with measured human plasma CL and the CL IVIVE predicted from its measured inputs. Use it to judge how far to trust calc_clhep for this chemotype: if IVIVE missed on the neighbours, expect it to miss here. Returns neighbours only, not a prediction for the query.
  • target_clintThe in-vitro CLint an assay must read for a compound to reach a target plasma clearance (mL/min/kg): calc_clhep run backwards, e.g.No findings

    Why it is in this group

    • Nothing in its name or description says what it does, so it is counted as a write.
    Description, as the server wrote it
    The in-vitro CLint an assay must read for a compound to reach a target plasma clearance (mL/min/kg): calc_clhep run backwards, e.g. to set a CLint cut-off for a screening cascade. Needs fu,mic and fu,p; refuses a target at or above the liver blood flow ceiling and returns that ceiling. Uncorrected IVIVE, so no error band.

This is not a safety rating, and no finding is not a safety guarantee. The groups and findings come from fixed checks of the tool definitions the server returned on the date shown, not from its code or what it does when called. How the checks work.

Install

Pinned to version 1.0.2. Values in angle brackets are yours to fill in.

claude mcp add --transport http ivive https://api.ivive.app/mcp/

Run in a terminal.

Claude Code permissions

Allow the reads, ask before a change, deny the deletes. Paste into .claude/settings.json.

.claude/settings.json
{
  "permissions": {
    "allow": [],
    "ask": [
      "mcp__ivive__predict_inputs",
      "mcp__ivive__calc_clhep",
      "mcp__ivive__target_clint",
      "mcp__ivive__input_sensitivity",
      "mcp__ivive__similar_drugs",
      "mcp__ivive__scale_to_human"
    ],
    "deny": []
  }
}

Tools that only read are allowed, tools that change things ask first, tools that delete or cancel are denied. It assumes the server is installed as ivive. Review it before you use it.